• Dr. Brooks along with Dr. Alain Litwin of Prisma Health and Clemson University are Co-PIs on an R01 study funded by AHRQ entitled The Development and Evaluation of a Patient-Centered Opioid Discharge Prescribing Guideline Within the Electronic Health Record of a Health System. The study uses a unique stepped-wedged units within Prisma Health System. The data structures for this study are based on the structures and processes developed for the OPDR.

• Dr. Brooks and Dr. Jennifer Trilk of the University of South Carolina School of Medicine-Greenville were funded by the Duke Endowment to retrospectivelyassess the cost-effectiveness of the Exercise is Medicine program developed for Prisma Health by Dr. Trilk. Retrospective data for diabetic, hypertensive, or obese patients are being drawn on the structures and processes developed for the OPDR.

• Drs. Trilk and Dr. Brooks were funded by the National Institute of Health in a R56 study entitled Implementingand Evaluating the Comprehensive Integration of Physical Activity into a Major Health System and ConnectingPatients to Community-Based Physical Activity Programs to build the data structures necessary for a prospective cost-effectiveness of the Exercise is Medicine program using an innovative step-wedged design across Prisma Health primary care practices. The data structure for this study are based on the data structure and processes developed with the OPDR.

• Drs. Brooks, Floyd, Chapman, and Thigpen received funding in 2020 on an R01 from AHRQ entitled Effects ofMusculoskeletal Surgery Rates on Outcomes to assess the cost, detriments, and benefits from Medicare’s perspective associated with higher early surgery rates for newly diagnosed patients with shoulder conditions.